Leena Patel Selected Research

6- ((3- ((4- (5- ((2- hydroxy- 2- (8- hydroxy- 2- oxo- 1,2- dihydroquinolin- 5- yl)ethyl)amino)pent- 1- yn- 1- yl)phenyl)carbamoyl)phenyl)sulfonyl)- 4- ((3- methoxyphenyl)amino)- 8- methylquinoline- 3- carboxamide

4/2014

The in vitro pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long acting β2-adrenoceptor agonist.

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Leena Patel Research Topics

Disease

4	Neoplasms (Cancer) 01/2022 - 08/2011
3	Intervertebral Disc Degeneration 10/2021 - 01/2018
3	Atrial Fibrillation 01/2021 - 01/2020
2	Back Pain (Backache) 10/2021 - 01/2018
2	Hematologic Neoplasms (Hematological Malignancy) 10/2016 - 04/2016
2	Hypoglycemia (Reactive Hypoglycemia) 01/2016 - 01/2013
2	Type 2 Diabetes Mellitus (MODY) 09/2013 - 12/2012
1	Gastroenteritis 01/2022
1	Sepsis (Septicemia) 01/2022
1	Bacterial Meningitis 01/2022
1	Shock 01/2022
1	Lung Neoplasms (Lung Cancer) 01/2022
1	Congenital Hypothyroidism (Cretinism) 01/2021
1	Cardiac Arrhythmias (Arrythmia) 01/2021
1	Congenital adrenal hyperplasia due to 21 hydroxylase deficiency 12/2019
1	Chronic Renal Insufficiency 01/2019
1	Turner Syndrome (Turner's Syndrome) 01/2019
1	Prader-Willi Syndrome (Syndrome, Prader-Willi) 01/2019
1	Low Back Pain (Lumbago) 06/2018
1	Acute Kidney Injury (Acute Renal Failure) 01/2018
1	Diabetes Insipidus 03/2017
1	Residual Neoplasm 03/2017
1	Rheumatoid Arthritis 10/2016
1	Hypercalcemia (Milk Alkali Syndrome) 02/2016
1	Hyperphosphatemia 02/2016
1	Seroma 01/2016
1	Hematoma 01/2016
1	Hyperinsulinism (Hyperinsulinemia) 01/2016
1	Breast Neoplasms (Breast Cancer) 01/2016
1	Wound Infection (Wound Infections) 01/2016
1	Necrosis 01/2016
1	Ecchymosis 01/2016
1	Strabismus (Squint) 04/2015
1	Stomach Neoplasms (Stomach Cancer) 01/2015
1	Diabetic Nephropathies (Diabetic Nephropathy) 07/2014
1	Chronic Obstructive Pulmonary Disease (COPD) 04/2014
1	Congenital Hyperinsulinism 01/2014
1	Obesity 09/2013
1	Wounds and Injuries (Trauma) 12/2012

Drug/Important Bio-Agent (IBA)

3	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2017 - 04/2016
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2019
2	Growth Hormone (Somatotropin)IBA 01/2019 - 08/2002
2	Dichlorodiphenyldichloroethane (DDD)IBA 06/2018 - 01/2018
2	Hormones (Hormone)IBA 03/2017 - 10/2004
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 07/2014 - 08/2011
1	LigandsIBA 01/2022
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2022
1	Purinergic P1 Receptors (Adenosine Receptor)IBA 01/2022
1	N(6)- (4- amino- 3- iodobenzyl)adenosine- 5'- N- methyluronamideIBA 01/2022
1	Narcotics (Narcotic Analgesics)IBA 10/2021
1	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 01/2021
1	AndrogensIBA 12/2019
1	TensinsIBA 01/2017
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2017
1	Parathyroid Hormone (Parathormone)IBA 02/2016
1	Sevelamer (RenaGel)FDA Link 02/2016
1	CalciumIBA 02/2016
1	CholesterolIBA 02/2016
1	LipidsIBA 02/2016
1	LDL CholesterolIBA 02/2016
1	Phosphates (Orthophosphate)IBA 02/2016
1	Glucagon (Glukagon)FDA Link 01/2016
1	Glucose (Dextrose)FDA LinkGeneric 01/2016
1	Botulinum Toxins (Botulinum Toxin)IBA 04/2015
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2014
1	Adenosine (Adenocard)FDA LinkGeneric 07/2014
1	NitritesIBA 07/2014
1	CytokinesIBA 07/2014
1	Adenosine A2B ReceptorIBA 07/2014
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2014
1	Type 4 Cyclic Nucleotide PhosphodiesterasesIBA 04/2014
1	Phosphodiesterase 4 InhibitorsIBA 04/2014
1	Bronchodilator Agents (Bronchodilators)IBA 04/2014
1	RoflumilastIBA 04/2014
1	6- ((3- ((4- (5- ((2- hydroxy- 2- (8- hydroxy- 2- oxo- 1,2- dihydroquinolin- 5- yl)ethyl)amino)pent- 1- yn- 1- yl)phenyl)carbamoyl)phenyl)sulfonyl)- 4- ((3- methoxyphenyl)amino)- 8- methylquinoline- 3- carboxamideIBA 04/2014
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2014
1	MaxepaIBA 01/2014
1	Diazoxide (Hyperstat)FDA Link 01/2014
1	Carboxylic AcidsIBA 09/2013
1	EnzymesIBA 09/2013
1	Messenger RNA (mRNA)IBA 09/2013
1	GlucokinaseIBA 12/2012
1	pyrazolopyridineIBA 12/2012
1	IndazolesIBA 12/2012

Therapy/Procedure

7	Therapeutics 01/2022 - 08/2011
3	Total Disc Replacement 10/2021 - 01/2018
3	Catheter Ablation 01/2021 - 01/2020
2	Catheters 01/2021 - 01/2020
2	Lymph Node Excision (Lymph Node Dissection) 01/2016 - 01/2015
1	Radiofrequency Ablation 01/2021
1	Spinal Fusion (Spondylosyndesis) 06/2018
1	Stem Cell Transplantation 01/2018
1	Adjuvant Radiotherapy 03/2017
1	Mastectomy (Mammectomy) 01/2016
1	Enteral Nutrition (Feeding, Tube) 01/2016
1	Segmental Mastectomy (Lumpectomy) 01/2016
1	Length of Stay 01/2016
1	Injections 04/2015
1	Gastrectomy 01/2015
1	Orchiopexy 12/2012